U.S. Based Cellular Therapy For TBI
The Only U.S.-Based Patented Cell Therapy for Traumatic Brain Injuries

An Innovative Approach to Traumatic Brain Injury Care

Signolii® reduces inflammation and swelling after brain injury. Supports injury recovery for athletes, veterans, vehicle accident victims, and individuals injured in accidents.

The therapy follows rigorous protocols, is administered in a controlled setting, and complies with FDA guidelines outlined in 21 CFR 1271.10, which define oversight under section 361 of the PHS Act and 21 CFR Part 1271.

Where It All Began

Signolii® began with a simple question. What if we could change the body's inflammatory response after a brain injury? After seeing how inflammation drives symptoms in both stroke and traumatic brain injury, we focused on a solution built to reduce swelling and support recovery.

Our work is personal. Years of repeated concussions can create real, life altering symptoms like anxiety, emotional instability, and persistent brain fog. After cellular therapy, we saw how quickly those symptoms can change when inflammation is addressed at the source.

Today, Signolii® Sports is built for both treatment and prevention, helping athletes recover faster and helping teams reduce the risk of long term post concussion issues before they spiral.

Streamlined, stress-free guidance.

What's The Consultation Like?

  1. Book a consultation to discuss your symptoms, injury history, and goals. Timing matters, so we'll help you understand when treatment may be most effective for your situation. Contact us at +1 (504) 294-8333.

Testimonial Videos

Real Patients, Real Results

Click To Fullscreen

Signolii® Sports | Ricky Wade Testimonial

“I could tell I was getting better and the people around me could tell”

Patient testimonial previewPatient testimonial preview

"Having them do the therapy with me was wonderful, it was a blessing.”

Signolii® Sports Makes a Difference

Common Causes of TBI

After a brain injury, the stroke or impact isn't always the biggest threat. The inflammation and swelling that follows often drives the lasting damage. Signolii® Sports focuses on reducing that inflammatory response, helping the brain move out of the danger phase and into repair. Timing matters. Choose Signolii® Sports.

Sports

Sports Injury

Repeated concussions can leave lasting inflammation. After 48 hours, earlier treatment tends to work best. That's Signolii®.

Stroke

Stroke

Stroke damage can spread quickly. Early treatment helps limit that spread and protect more brain tissue. Signolii® Sports is ready.

Vehicle Crashes

Vehicle Crashes

Vehicles crashes can cause sudden brain swelling. Signolii® Sports helps reduce that swelling early, giving the brain a better chance to recover.

The Science Behind Signolii® Sports

After a brain injury, the stroke or impact isn't always the biggest threat. The inflammation and swelling that follows often drives the lasting damage. Signolii® Sports focuses on reducing that inflammatory response, helping the brain move out of the danger phase. Timing matters.

What Treatment Day Looks Like

After the tissue has been processed by the lab, we setup the patients IV infusion for 1 Hour & 45 minutes. In some cases, follow-up infusions may be needed.

Why Patients Choose
Signolii® Sports

The approach is patented, supports treatment and prevention, and most patients do not need to stop medications.

Professional & Friendly Team

Meet Our Team

Neurologist

Dr. Alan Cole

Dr. Alan Cole

Neurology Specialist

A fellowship-trained neurologist who has spent 9+ years pioneering cellular infusion innovation, leading the creation of the only U.S.-based patented cell-therapy platform for traumatic brain injury.

You have questions, we have answers.

Frequently Asked Questions

  1. Signolii is designed for adults dealing with concussion related symptoms and traumatic brain injury, whether from sports, accidents, or repeated impact exposure.

Considering Signolii® Sports For Your TBI?

Set up a consult and review the treatment schedule, travel plans and next steps.

+1 (504) 294-8333